Selective treatment of acute myeloid leukemia targeting the activated conformation of integrin beta2 with [225Ac]Macropa-PEG4-7065.

Anju Wadhwa, Haley Johnson, Kamal Mandal, Kondapa Bobba, Anil Bidkar, Athira Raveendran, Ellis Mayne, Sham Rampersaud, Amrik S. Kang, Megha Basak, Marina Lopez-Alvarez, Sanghee Lee, Veronica Steri, David Wilson, Henry VanBrocklin, Youngho Seo, Jarrett J. Adams, Sachdev S. Sidhu, Arun Wiita, Robert Flavell. Selective treatment of acute myeloid leukemia targeting the activated conformation of integrin beta2 with [225Ac]Macropa-PEG4-7065. Nuclear Medicine and Biology. 2025 Nov 1; 150:109544.